But it usually happens after months or years of latent TB infection. Active TB disease may happen right after primary infection. Germs cause disease throughout the lungs or other parts of the body. Active TB disease happens when the immune system can't control an infection. There are no symptoms during latent TB infection.Īctive TB disease. The germs can't do any more harm if the immune system keeps them under control. Immune system cells build a wall around lung tissue with TB germs. Primary infection is usually followed by the stage called latent TB infection. Some people may get flu-like symptoms, such as: Most people don't have symptoms during a primary infection. But some captured germs may still survive and multiply. The immune system may completely destroy the germs. Immune system cells find and capture the germs. The first stage is called the primary infection. A TB infection may be in one of three stages. When tuberculosis (TB) germs survive and multiply in the lungs, it is called a TB infection.
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